Ethambutol-d4

• Description:

  Ethambutol-d4 is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

• Product Name Alternative:

  Emb-d4

• UNSPSC:

  12352211

• Target:

  Antibiotic; Bacterial; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection; Others

• Field of Research:

  Infection

• Purity:

  98.12

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC[C@@H] (CO) NC ([2H]) ([2H]) C ([2H]) ([2H]) N[C@H] (CO) CC

• Molecular Formula:

  C10H20D4N2O2

• Molecular Weight:

  208.33

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Ethambutol. Tuberculosis (Edinb), 2008. 88 (2) : p. 102-5.|[3]Rastogi, N., V. Labrousse, and K.S. Goh, In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages. Curr Microbiol, 1996. 33 (3) : p. 167-75.|[4]Kaur, D. and G.K. Khuller, In vitro, ex-vivo and in vivo activities of ethambutol and sparfloxacin alone and in combination against mycobacteria. Int J Antimicrob Agents, 2001. 17 (1) : p. 51-5.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  1129526-19-7