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Ethambutol-d4

CAT: 0804-HY-B0535S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0535S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ethambutol-d4 is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.
CAS Number
1129526-19-7
Product Name Alternative
Emb-d4
UNSPSC
12352211
Target
Antibiotic; Bacterial; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Field of Research
Infection
Purity
98.12
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC[C@@H](CO)NC([2H])([2H])C([2H])([2H])N[C@H](CO)CC
Molecular Formula
C10H20D4N2O2
Molecular Weight
208.33
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Ethambutol. Tuberculosis (Edinb), 2008. 88 (2) : p. 102-5.|[3]Rastogi, N., V. Labrousse, and K.S. Goh, In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages. Curr Microbiol, 1996. 33 (3) : p. 167-75.|[4]Kaur, D. and G.K. Khuller, In vitro, ex-vivo and in vivo activities of ethambutol and sparfloxacin alone and in combination against mycobacteria. Int J Antimicrob Agents, 2001. 17 (1) : p. 51-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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