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Ornidazole-d5

CAT: 0804-HY-B0508SSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0508SSize:5 mg
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Description
Ornidazole-d5 is deuterium labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease[1][2][3].
CAS Number
2747915-64-4
Product Name Alternative
Ro 7-0207-d5
UNSPSC
12352005
Target
Antibiotic; Bacterial; Hedgehog; Isotope-Labeled Compounds; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Solubility
10 mM in DMSO
Smiles
CC1=NC=C([N+]([O-])=O)N1C([2H])([2H])C(C([2H])([2H])Cl)([2H])O
Molecular Formula
C7H5D5ClN3O3
Molecular Weight
224.66
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Goldstein, E.J., V.L. Sutter, and S.M. Finegold, Comparative susceptibilities of anaerobic bacteria to metronidazole, ornidazole, and SC-28538. Antimicrob Agents Chemother, 1978. 14 (4) : p. 609-13.|[3]Rutgeerts, P., et al., Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology, 2005. 128 (4) : p. 856-61.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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