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Ornidazole

CAT: 0804-HY-B0508-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0508-01Size:500 mg
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Description
Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease[1][2][3].
CAS Number
16773-42-5
Product Name Alternative
Ro 7-0207
UNSPSC
12352005
Hazard Statement
H302
Target
Antibiotic; Bacterial; Hedgehog; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/ornidazole.html
Purity
99.97
Solubility
DMSO : ≥ 100 mg/mL|H2O : 10 mg/mL (ultrasonic)
Smiles
CC1=NC=C([N+]([O-])=O)N1CC(CCl)O
Molecular Formula
C7H10ClN3O3
Molecular Weight
219.63
Precautions
H302
References & Citations
[1]Rutgeerts, P., et al., Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology, 2005. 128 (4) : p. 856-61.|[2]Goldstein, E.J., V.L. Sutter, and S.M. Finegold, Comparative susceptibilities of anaerobic bacteria to metronidazole, ornidazole, and SC-28538. Antimicrob Agents Chemother, 1978. 14 (4) : p. 609-13.|[3]Evyapan G, et al., Ornidazole suppresses CD133+ melanoma stem cells via inhibiting hedgehog signaling pathway and inducing multiple death pathways in a mouse model. Croat Med J. 2022 Oct 31;63 (5) :461-474.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Launched

Alternative Products

CatalogName
B1996-5.1Ornidazole

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