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Levofloxacin-13C, d3

CAT: 0804-HY-B0330S2Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0330S2Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Levofloxacin-13C, d3 is the 13C- and deuterium labeled Levofloxacin.
CAS Number
1261398-33-7
Product Name Alternative
(-) -Ofloxacin-13C, d3
UNSPSC
12352005
Hazard Statement
H302, H317, H334, H361, H362
Target
Antibiotic; Bacterial; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Purity
98.76
Solubility
10 mM in DMSO|DMSO : 10mg/mL (ultrasonic) |H2O : ≥ 5mg/mL
Smiles
O=C1C2=CC(F)=C(N3CCN(CC3)[13C]([2H])([2H])[2H])C4=C2N(C=C1C(O)=O)[C@@H](C)CO4
Molecular Formula
C17 13CH17D3FN3O4
Molecular Weight
365.38
Precautions
H302, H317, H334, H361, H362
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.|[2]Lee, B.T., et al., Efficacy of Levofloxacin in the Treatment of BK Viremia: A Multicenter, Double-Blinded, Randomized, Placebo-Controlled Trial. Clin J Am Soc Nephrol, 2014.|[3]Pradeep, A.R., et al., Clinical and microbiological effects of levofloxacin in the treatment of chronic periodontitis: a randomized, placebo-controlled clinical trial. J Investig Clin Dent, 2014.|[4]Siva, R., et al., Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial. Int J Chron Obstruct Pulmon Dis, 2014. 9: p. 179-86.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported