Products for Research Use Only
RegisterLogin

Methylprednisolone-d2

CAT: 0804-HY-B0260S4-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0260S4-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Methylprednisolone-d2 is the deuterium labeled Methylprednisolone. Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels[3][4].
Product Name Alternative
U 7532-d2
UNSPSC
12352211
Target
Autophagy; Glucocorticoid Receptor; SARS-CoV
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Autophagy; Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Others
Purity
99.11
Solubility
10 mM in DMSO
Smiles
O=C1C=C[C@]2(C)[C@@]3([H])[C@@H](O)C[C@]4(C)[C@@](O)(C(C([2H])([2H])O)=O)CC[C@@]4([H])[C@]3([H])C[C@H](C)C2=C1
Molecular Formula
C22H28D2O5
Molecular Weight
376.48
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Bracken, M.B., et al., A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study. N Engl J Med, 1990. 322 (20) : p. 1405-11.|[3]Strupp, M., et al., Methylprednisolone, valacyclovir, or the combination for vestibular neuritis. N Engl J Med, 2004. 351 (4) : p. 354-61.|[4]Zhen Xiang, et al. Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels. Int J Biol Sci 2020; 16 (13) :2382-2391.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-B0260-01Methylprednisolone
HY-B1900-01Methylprednisolone succinate
HY-B0260S-01Methylprednisolone-d3
HY-B0260S3Methylprednisolone-d7
HY-B0260S2-01Methylprednisolone-d4
HY-103025-01Methylprednisolone aceponate
HY-13681-01Methylprednisolone acetate
HY-B0260R-01Methylprednisolone (Standard)
HY-103025R-01Methylprednisolone aceponate (Standard)
HY-B1900R-01Methylprednisolone succinate (Standard)

Alternative Products

CatalogName
TMID-0145-01Methylprednisolone-d2
A4233-1000Methylprednisolone
80-1219Methylprednisolone-HRP

Popular Products