Norgestrel-d6

• Description:

  Norgestrel-d6 is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives. Norgestrel-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• UNSPSC:

  12352211

• Hazard Statement:

  H302+H312+H332, H315, H319, H351, H360, H362

• Target:

  Isotope-Labeled Compounds; Progesterone Receptor

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Others; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Endocrinology

• Purity:

  99.53

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@]1(CC[C@]2([C@@]3(CC([2H])(C4=C(C(C([2H])(C[C@@]4([C@]3(CC[C@@]21CC)[H])[2H])[2H])=O)[2H])[2H])[H])[H])C#C

• Molecular Formula:

  C21H22D6O2

• Molecular Weight:

  318.48

• Precautions:

  H302+H312+H332, H315, H319, H351, H360, H362

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Gallos, I.D., et al., Oral progestogens vs levonorgestrel-releasing intrauterine system for endometrial hyperplasia: a systematic review and metaanalysis. Am J Obstet Gynecol, 2010. 203 (6) : p. 547 e1-10.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  [2376035-98-0]