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Norgestrel-d6

CAT: 0804-HY-B0257S1-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0257S1-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Norgestrel-d6 is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives. Norgestrel-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[2376035-98-0]
UNSPSC
12352211
Hazard Statement
H302+H312+H332, H315, H319, H351, H360, H362
Target
Isotope-Labeled Compounds; Progesterone Receptor
Type
Isotope-Labeled Compounds
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Purity
99.53
Solubility
10 mM in DMSO
Smiles
O[C@]1(CC[C@]2([C@@]3(CC([2H])(C4=C(C(C([2H])(C[C@@]4([C@]3(CC[C@@]21CC)[H])[2H])[2H])=O)[2H])[2H])[H])[H])C#C
Molecular Formula
C21H22D6O2
Molecular Weight
318.48
Precautions
H302+H312+H332, H315, H319, H351, H360, H362
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Gallos, I.D., et al., Oral progestogens vs levonorgestrel-releasing intrauterine system for endometrial hyperplasia: a systematic review and metaanalysis. Am J Obstet Gynecol, 2010. 203 (6) : p. 547 e1-10.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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