Levonorgestrel-d8

• Description :

  Levonorgestrel-d8 is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives[1][2]. Levonorgestrel-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Product Name Alternative :

  D-Norgestrel-D8

• UNSPSC :

  12352211

• Target :

  Isotope-Labeled Compounds; Progesterone Receptor

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Others; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Endocrinology

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C([2H])([2H])C[C@]2([2H])[C@@]3([H])CC[C@]4(CC)[C@@](C#C)(O)C([2H])([2H])C[C@@]4([H])[C@]3([H])CC([2H])([2H])C2=C1[2H]

• Molecular Formula :

  C21H20D8O2

• Molecular Weight :

  320.50

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Gallos, I.D., et al., Oral progestogens vs levonorgestrel-releasing intrauterine system for endometrial hyperplasia: a systematic review and metaanalysis. Am J Obstet Gynecol, 2010. 203 (6) : p. 547 e1-10.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported