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Carbamazepine-d2

CAT: 0804-HY-B0246S1Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0246S1Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Carbamazepine-d2 is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant agent.
CAS Number
1189902-21-3
Product Name Alternative
CBZ-d2; NSC 169864-d2
UNSPSC
12352005
Target
Autophagy; Isotope-Labeled Compounds; Mitophagy; Sodium Channel
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; Membrane Transporter/Ion Channel; Others
Field of Research
Neurological Disease; Cancer
Solubility
10 mM in DMSO
Smiles
NC(N1C2=CC=CC=C2C([2H])=C([2H])C3=CC=CC=C31)=O
Molecular Formula
C15H10D2N2O
Molecular Weight
238.28
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Willow, M. and W.A. Catterall, Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine. Mol Pharmacol, 1982. 22 (3) : p. 627-35.|[3]Okada, M., et al., Biphasic effects of carbamazepine on the dopaminergic system in rat striatum and hippocampus. Epilepsy Res, 1997. 28 (2) : p. 143-53.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported