Products for Research Use Only
RegisterLogin

Trandolaprilate-d6

CAT: 0804-HY-A0116S1Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-A0116S1Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Trandolaprilate-d6 is the deuterium labeled Trandolaprilate[1]. Trandolaprilate is a potent angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity[2][3].
UNSPSC
12352005
Target
Angiotensin-converting Enzyme (ACE) ; Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(C([C@@H](N[C@H](C(O)=O)CC([2H])C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C)=O)[C@@]3([H])CCCC[C@]3([H])C1)O
Molecular Formula
C22H24D6N2O5
Molecular Weight
408.52
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Millet D, et al. Effects of angiotensins on cellular hypertrophy and c-fos expression in cultured arterial smooth muscle cells. Eur J Biochem. 1992 Jun 1;206 (2) :367-72.|[3]Al-Hawash LA, et al. Stability-indicating HPLC determination of trandolapril in bulk drug and pharmaceutical dosage forms. Int J Anal Chem. 20152015:820517.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-A0116-01Trandolaprilate
HY-A0116ATrandolaprilate (hydrate)
HY-A0116S-01Trandolaprilate-d5
HY-A0116R-01Trandolaprilate (Standard)
HY-158254S(Rac) -Trandolaprilate-d5
HY-110225-01Levetiracetam-d6 (ring-d6)
HY-N0893STetrahydrocurcumin-d6
HY-W750155Tetramethrin-d6
HY-W744578Taurolidine-d6
HY-W744275Tipelukast-d6

Alternative Products

CatalogName
MBS5767768Trandolaprilate D5
MBS5814753Trandolaprilate hydrate
CS-O-59102Fruquintinib-d6 (Dimethoxy-d6)
UYB80274-01Bezafibrate-d6 (dimethyl-d6)
TMIJ-0459-01Methamidophos-d6 (dimethyl-d6)
RM-P052032-01Pentoxifylline-D6 (Dimethyl-D6)
TRC-M260801-5MGMethoxychlor-d6 (dimethoxy-d6)
AR-T06190-01Tucatinib-d6 (Irbinitinib-d6)
CS-O-48182Tivozanib-d6 (Dimethoxy-d6)
TMIJ-0478-01Pirimicarb-d6 (dimethylcarbamate-d6)

Popular Products