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Nitrofurantoin (sodium)

CAT: 0804-HY-A0090ASize: 1 EachDry Ice: NoHazardous: No
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Description
Nitrofurantoin sodium is a potent and orally active antibacterial agent. Nitrofurantoin sodium acts as an antibiotic. Nitrofurantoin sodium can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections[1][2].
CAS Number
54-87-5
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nitrofurantoin-sodium.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(CN1/N=C/C2=CC=C([N+]([O-])=O)O2)=O.[Na]
Molecular Formula
C8H6N4NaO5
Molecular Weight
261.15
References & Citations
[1]Huttner A, et al. Nitrofurantoin revisited: a systematic review and meta-analysis of controlled trials. J Antimicrob Chemother. 2015 Sep;70 (9) :2456-64. |[2]Garau J. Other antimicrobials of interest in the era of extended-spectrum beta-lactamases: fosfomycin, nitrofurantoin and tigecycline. Clin Microbiol Infect. 2008 Jan;14 Suppl 1:198-202.|[3]Linus Sandegren, et al. Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli. J Antimicrob Chemother. 2008 Sep;62 (3) :495-503.|[4]Xiaodong Wang, et al. Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2. Drug Metab Dispos. 2007 Feb;35 (2) :268-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched