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Maleic hydrazide-d2

CAT: 0804-HY-59354S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-59354S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Maleic hydrazide-d2 is the deuterium labeled Maleic hydrazide[1]. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins[2][3].
CAS Number
2398483-97-9
UNSPSC
12352005
Hazard Statement
H315, H319, H335, H341
Target
DNA/RNA Synthesis
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.31
Solubility
10 mM in DMSO
Smiles
O=C1C([2H])=C([2H])C(NN1)=O
Molecular Formula
C4H2D2N2O2
Molecular Weight
114.10
Precautions
H315, H319, H335, H341
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Venezian A, et al. The Influence of the Plant Growth Regulator Maleic Hydrazide on Egyptian Broomrape Early Developmental Stages and Its Control Efficacy in Tomato under Greenhouse and Field Conditions. Front Plant Sci. 2017;8:691. Published 2017 May 16.|[3]Swietlińska Z, et al. Cytotoxic effects of maleic hydrazide. Mutat Res. 197855 (1) :15-30.|[4]Yurdakok B, et al. Cytotoxic effects of etephon and maleic hydrazide in Vero, Hep2, HepG2 cells. Drug Chem Toxicol. 201437 (4) :459-465.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported