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Maleic hydrazide

CAT: 0804-HY-59354-01Size: 50 gDry Ice: NoHazardous: No
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CAT#:0804-HY-59354-01Size:50 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins[1][2].
CAS Number
123-33-1
UNSPSC
12352005
Hazard Statement
H315, H319, H335, H341
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/maleic-hydrazide.html
Purity
99.98
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1C=CC(NN1)=O
Molecular Formula
C4H4N2O2
Molecular Weight
112.09
Precautions
H315, H319, H335, H341
References & Citations
[1]Venezian A, et al. The Influence of the Plant Growth Regulator Maleic Hydrazide on Egyptian Broomrape Early Developmental Stages and Its Control Efficacy in Tomato under Greenhouse and Field Conditions. Front Plant Sci. 2017;8:691. Published 2017 May 16.|[2]Swietlińska Z, et al. Cytotoxic effects of maleic hydrazide. Mutat Res. 1978;55 (1) :15-30.|[3]Yurdakok B, et al. Cytotoxic effects of etephon and maleic hydrazide in Vero, Hep2, HepG2 cells. Drug Chem Toxicol. 2014;37 (4) :459-465.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Maleic Hydrazide

Maleic hydrazide is a pyridazinone.

CAS Number123-33-1
PubChem CID21954
IUPAC Name1,2-dihydropyridazine-3,6-dione
Molecular FormulaC4H4N2O2
Molecular Weight112.09
XLogP-0.8
Topological Polar Surface Area58.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Heavy Atom Count8
Formal Charge0
Complexity143
SMILES
C1=CC(=O)NNC1=O
InChI
InChI=1S/C4H4N2O2/c7-3-1-2-4(8)6-5-3/h1-2H,(H,5,7)(H,6,8)
InChIKey
BGRDGMRNKXEXQD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Maleic Hydrazide
CAS: 123-33-1
CID: 21954
Formula: C4H4N2O2
MW: 112.09
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight112.09
XLogP3-0.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass112.027277375
Monoisotopic Mass112.027277375
Topological Polar Surface Area58.2 Ų
Heavy Atom Count8
Formal Charge0
Complexity143
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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