2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite

2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite

• CAS Number: 1190089-70-3
• UNSPSC Description: 2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/2-fluoro-2-deoxy-ara-u-3-phosphoramidite.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C=C1)NC(N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H]2F)=O
• Molecular Weight: 748.78
• References & Citations: [1]Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported