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AcLys-PABC-VC-Aur0101 intermediate-1

CAT: 0804-HY-48668Size: 1 EachDry Ice: NoHazardous: No
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Description
AcLys-PABC-VC-Aur0101 intermediate-1 is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate[1].
CAS Number
1609108-48-6
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aclys-pabc-vc-aur0101-intermediate-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CCCCNC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O)=O
Molecular Formula
C41H53N7O8
Molecular Weight
771.90
References & Citations
[1]Kenneth John DIRICO, et al. Spliceostatin analogs. WO2014068443A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cleavable Linker

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T87774-01AcLys-PABC-VC-Aur0101 intermediate-1
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A19371-5AcLys-PABC-VC-Aur0101 5mg
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A19371-10AcLys-PABC-VC-Aur0101 10mg
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