AcLys-PABC-VC-Aur0101
CAT:
804-HY-111554-01
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AcLys-PABC-VC-Aur0101
- CAS Number: 1438851-17-2
- UNSPSC Description: AcLys-PABC-VC-Aur0101 is a agent-linker conjugate for ADC (anti-CXCR4 ADC) with potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the cleavable linker AcLys-PABC-VC[1].
- Target Antigen: Drug-Linker Conjugates for ADC; Microtubule/Tubulin
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/AcLys-PABC-VC-Aur0101.html
- Purity: 98.49
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: CC(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(NC(C)(C)C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@H]([C@@H]([C@H](C(N[C@@H](CC3=CC=CC=C3)C4=NC=CS4)=O)C)OC)CCC2)=O)=O)=O)=O)C=C1)=O)=O)=O)=O
- Molecular Weight: 1318.67
- References & Citations: [1]Costa MJ, et al. Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates. Sci Rep. 2019 Feb 21;9(1):2443.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported