L2H2-6OTD intermediate-3

• Description :

  L2H2-6OTD intermediate-3 is an intermediate for the synthesis of L2H2-6OTD (HY-148200) and can be used for ADC preparation. L2H2-6OTD, a telomestatin analog with telomerase inhibitory activity (IC50: 15 nM) [1].

• UNSPSC :

  12352005

• Target :

  Drug Intermediate

• Type :

  Reference compound

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/l2h2-6otd-intermediate-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N[C@@H](CO)C1=NC(C2=NC(C(OC)=O)=CO2)=CO1)[C@@H](CCCCNC(OC(C)(C)C)=O)NC(OCC3=CC=CC=C3)=O

• Molecular Formula :

  C29H37N5O10

• Molecular Weight :

  615.63

• References & Citations :

  [1]Doi T, et al. Total synthesis of (R) -telomestatin. Org Lett. 2006 Aug 31;8 (18) :4165-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported