L2H2-6OTD intermediate-3

• UNSPSC Description:

  L2H2-6OTD intermediate-3 is an intermediate for the synthesis of L2H2-6OTD (HY-148200) and can be used for ADC preparation. L2H2-6OTD, a telomestatin analog with telomerase inhibitory activity (IC50: 15 nM)[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/l2h2-6otd-intermediate-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@@H](CO)C1=NC(C2=NC(C(OC)=O)=CO2)=CO1)[C@@H](CCCCNC(OC(C)(C)C)=O)NC(OCC3=CC=CC=C3)=O

• Molecular Weight:

  615.63

• References & Citations:

  [1]Doi T, et al. Total synthesis of (R)-telomestatin. Org Lett. 2006 Aug 31;8(18):4165-7.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported