Chlorthalidone impurity

• Description :

  Chlorthalidone impurity is a metabolite of Chlorthalidone (HY-15833) . Chlorthalidone is a thiazide-like diuretic used to treat hypertension[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Drug Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/chlorthalidone-impurity.html

• Purity :

  99.68

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=C(O)C1=CC=CC=C1C(C2=CC=C(Cl)C(S(=O)(N)=O)=C2)=O

• Molecular Formula :

  C14H10ClNO5S

• Molecular Weight :

  339.75

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Bauer J, et al. Stability-indicating assay for chlorthalidone formulation: evaluation of the USP analysis and a high-performance liquid chromatographic analysis. J Pharm Sci. 1983 Aug;72 (8) :924-8.|[2]Barrios V, et al. Which thiazide to choose as add-on therapy for hypertension? Integr Blood Press Control. 2014 Jul 30;7:35-47.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [5270-74-6]