Chlorthalidone impurity

• UNSPSC Description:

  Chlorthalidone impurity is a metabolite of Chlorthalidone (HY-15833). Chlorthalidone is a thiazide-like diuretic used to treat hypertension[1][2].

• Target Antigen:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/chlorthalidone-impurity.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)C1=CC=CC=C1C(C2=CC=C(Cl)C(S(=O)(N)=O)=C2)=O

• Molecular Weight:

  339.75

• References & Citations:

  [1]Bauer J, et al. Stability-indicating assay for chlorthalidone formulation: evaluation of the USP analysis and a high-performance liquid chromatographic analysis. J Pharm Sci. 1983 Aug;72(8):924-8.|[2]Barrios V, et al. Which thiazide to choose as add-on therapy for hypertension? Integr Blood Press Control. 2014 Jul 30;7:35-47.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  5270-74-6