Olmesartan impurity

• Description :

  Olmesartan impurity is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist has the potential for high blood pressure study[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Angiotensin Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/olmesartan-impurity.html

• Purity :

  85.0

• Solubility :

  10 mM in DMSO

• Smiles :

  OCC1=CC=C(C2=CC=CC=C2C3=NN=NN3C(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)C=C1

• Molecular Formula :

  C33H26N4O

• Molecular Weight :

  494.59

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. J Pharmacol Sci. 2016 Jul;131 (3) :190-7.|[2]Tanno T, et al. Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure: Its Beneficial Effects on ACE2/Ang (1-7) /Mas Axis and NADPH Oxidase Expression. J Cardiovasc Pharmacol. 2016 Jun;67 (6) :503-9.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  AT1 Receptor

• CAS Number :

  [154709-18-9]