Chlorthalidone-d4

• Description :

  Chlorthalidone-d4 is the deuterium labeled Chlorthalidone. Chlorthalidone is a thiazide-like diuretic used to treat hypertension.

• CAS Number :

  [1794941-44-8]

• UNSPSC :

  12352005

• Target :

  Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Others

• Field of Research :

  Cardiovascular Disease

• Purity :

  98.49

• Solubility :

  DMSO : 41 mg/mL (ultrasonic; warming)

• Smiles :

  OC1(C2=CC(S(N)(=O)=O)=C(C=C2)Cl)C3=C([2H])C([2H])=C([2H])C([2H])=C3C(N1)=O

• Molecular Formula :

  C14H7D4ClN2O4S

• Molecular Weight :

  342.79

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Barrios V, et al. Which thiazide to choose as add-on therapy for hypertension? Integr Blood Press Control. 2014 Jul 30;7:35-47.; Ettinger B, et al. Chlorthalidone reduces calcium oxalate calculous recurrence but magnesium hydroxide does not. J Urol. 1988 Apr;139 (4) :679-84.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported