TES-d15

TES-d15

• CAS Number: 1219794-63-4
• UNSPSC Description: TES-d15 is the deuterium labeled TES[1]. TES is a buffering agent (pKa=7.550 at 25°C). TES is one of the Good's buffers, the buffer capacity ranging pH 6.8-8.2[2][3].
• Target Antigen: Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Others
• Field of Research: Others
• Solubility: 10 mM in DMSO
• Smiles: O=S(C([2H])([2H])C([2H])([2H])N([2H])C(C([2H])([2H])O[2H])(C([2H])([2H])O[2H])C([2H])([2H])O[2H])(O[2H])=O
• Molecular Weight: 244.34
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]N E Good, et al. Hydrogen ion buffers for biological research. Biochemistry. 1966 Feb;5(2):467-77.|[3]A Itagaki, et al. Tes and HEPES buffers in mammalian cell cultures and viral studies: problem of carbon dioxide requirement. Exp Cell Res. 1974 Feb83(2):351-61.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported