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D15

CAT: 0931-TP3764-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3764-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
251939-41-0
Target
IGluR
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Bioactivity
D15 is a peptide containing a 15-amino acid sequence of dynamitin, acting as an AMPAR endocytosis inhibitor. It effectively obstructs the interaction between dynamitin and amphiphysin 1 and 2. D15 significantly enhances the amplitude of AMPAR excitatory postsynaptic currents (EPSC) in the medium spiny neurons (MSNs) of Sapap3KO mice. It is utilized in research on neuropsychiatric disorders.
Smiles
C(=O)([C@H]1N(C(=O)[C@@H]2CCCN2)CCC1)N3[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(=O)N5[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N6[C@H](C(=O)N7[C@H](C(NCC(O)=O)=O)CCC7)CCC6)C)=O)CCCNC(=N)N)=O)CC(N)=O)=O)CCC5)CCCNC(=N)N)=O)CO)=O)CCC4)[C@H](C)C)=O)CCC(N)=O)=O)CCC3
Molecular Formula
C69H111N23O19
Molecular Weight
1566.76
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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