Iroxanadine (sulfate)

• UNSPSC Description:

  Iroxanadine (BRX 005) sulfate is a vasculoprotector. Iroxanadine is a p38 kinase and HSP protein dual activator. Iroxanadine sulfate has the potential for atherosclerosis and vascular diseases research[1].

• Target Antigen:

  HSP; p38 MAPK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;MAPK/ERK Pathway;Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/iroxanadine-sulfate.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S(O)(O)=O.C1(NC(C2=CN=CC=C2)=NOC1)CN3CCCCC3

• Molecular Weight:

  358.41

• References & Citations:

  [1]Denes L, et al. Reverse regulation of endothelial cells and myointimal hyperplasia on cell proliferation by a heatshock protein-coinducer after hypoxia. Stroke. 2008 Mar;39(3):1022-4.|[2]Kabakov AE, et al. Pharmacological attenuation of apoptosis in reoxygenated endothelial cells. Cell Mol Life Sci. 2004 Dec;61(24):3076-86.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  276690-61-0