Iroxanadine

• Description :

  Iroxanadine (BRX 005) is a vasculoprotector. Iroxanadine is a p38 kinase and HSP protein dual activator. Iroxanadine has the potential for atherosclerosis and vascular diseases research[1].

• CAS Number :

  [276690-58-5]

• Product Name Alternative :

  (-) -BRX 005; (-) -BRX 235

• UNSPSC :

  12352005

• Target :

  HSP; p38 MAPK

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; MAPK/ERK Pathway; Metabolic Enzyme/Protease

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/iroxanadine.html

• Smiles :

  C1(C2=CC=CN=C2)=NOCC(CN3CCCCC3)N1

• Molecular Formula :

  C14H20N4O

• Molecular Weight :

  260.33

• References & Citations :

  [1]Denes L, et al. Reverse regulation of endothelial cells and myointimal hyperplasia on cell proliferation by a heatshock protein-coinducer after hypoxia. Stroke. 2008 Mar;39 (3) :1022-4.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1