NIBR-17

• UNSPSC Description:

  NIBR-17 is a pan-class I PI3K inhibitor with suitable pharmacokinetic properties and inhibits tumor growth[1].

• Target Antigen:

  PI3K

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nibr-17.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC1=NC=C(C2=NC(N3CCOCC3)=NC(NC4=CC=C(OC)N=C4)=C2)C=N1

• Molecular Weight:

  380.40

• References & Citations:

  [1]Burger MT, et al. Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors. ACS Med Chem Lett. 2010 Oct 13;2(1):34-8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  944396-88-7