ES9-17

CAT: 0804-HY-131683-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-131683-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
ES9-17 is an analog of ES9 (endosidin9), which is an inhibitor of clathrin heavy chain (CHC) . ES9-17 is an inhibitor of clathrin-mediated endocytosis (CME), a major route for internalization of plasma membrane proteins and molecules from the extracellular environment in plants. ES9-17 inhibits the uptake of transferrin and FM4-64. ES9-17 also inhibits root growth of Arabidopsis seedings[1][2].
CAS Number
[55854-43-8]
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Clathrin; Dynamin
Type
Reference compound
Related Pathways
Cytoskeleton
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/es9-17.html
Concentration
10mM
Purity
99.87
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(Br)S1)(NC2=CC=CC=C2)=O
Molecular Formula
C10H8BrNO2S2
Molecular Weight
318.21
Precautions
H302, H312, H332
References & Citations
[1]Dejonghe W, et al. Disruption of endocytosis through chemical inhibition of clathrin heavy chain function. Nat Chem Biol. 2019 Jun;15 (6) :641-649. |[2]Huang L, et al. Progress in using chemical biology as a tool to uncover novel regulators of plant endomembrane trafficking. Curr Opin Plant Biol. 2019 Dec;52:106-113.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-16590417,17-Dimethyllinoleic acid
HY-W588181-0117β-Carboxy-17-desoxydexamethasone
HY-146915S17:0-17:1-17:0 TG-d5
HY-W46025617-Methoxy-17-oxoheptadecanoic acid
HY-10349517-PA
HY-N160617α-Thevebioside
HY-168062ZYZ-17
HY-N12428-0117-Hydroxyjolkinolide A
HY-149698Tyrosinase-IN-17
HY-126787-0117-Hydroxyventuricidin A

Alternative Products

CatalogName
MBS5807025ES9-17
MBS393792-01Heptadecanoic-17,17,17-D3 Acid
138536-01Cytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17)
138536-AF-PECytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (PE)
MBS6122208-01Cytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (APC)
MBS6122209-01Cytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (Biotin)
MBS6122210-01Cytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (FITC)
138536-AF-HRPCytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (HRP)
MBS6122207-01Cytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (AP)
MBS343180-01Interleukin-17 (IL-17)

Popular Products