Products for Research Use Only
RegisterLogin

Tegoprazan-d6

CAT: 0804-HY-17623SSize: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-17623SSize:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Tegoprazan (CJ-12420; RQ-00000004), a potassium-competitive acid blocker, is a reversible, oral active and highly selective inhibitor of gastric H+/K+-ATPase that could control gastric acid secretion and motility, with IC50 values ranging from 0.29-0.52 μM for porcine, canine, and human H+/K+-ATPases in vitro. Tegoprazan significantly improves colitis in mice and enhances the intestinal epithelial barrier function. Tegoprazan is promising for research of Inflammatory bowel, gastric acid-related, motilityimpaired diseases[1][2][3].
Product Name Alternative
CJ-12420-d6; RQ-00000004-d6
UNSPSC
12352005
Target
Na+/K+ ATPase; Proton Pump
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
CC1=NC2=C(C=C(C=C2N1)C(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)O[C@H]3CCOC4=C3C(F)=CC(F)=C4
Molecular Formula
C20H13D6F2N3O3
Molecular Weight
393.42
References & Citations
[1]Takahashi N, Take Y. Tegoprazan, a Novel Potassium-Competitive Acid Blocker to Control Gastric Acid Secretion and Motility. J Pharmacol Exp Ther. 2018 Feb;364 (2) :275-286.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-17623-01Tegoprazan
HY-17623C-01(R) -Tegoprazan
HY-17623DTegoprazan (Benzoate)
HY-17623R-01Tegoprazan (Standard)
HY-110225-01Levetiracetam-d6 (ring-d6)
HY-N0893STetrahydrocurcumin-d6
HY-W750155Tetramethrin-d6
HY-W744578Taurolidine-d6
HY-W744275Tipelukast-d6
HY-W704964-01Dimethylcyanamide-d6

Alternative Products

CatalogName
CS-O-43027Tegoprazan-d6
BA6936-50Tegoprazan
RM-T051608-01Tegoprazan Impurity 8 ((R) -Tegoprazan)

Popular Products