Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine (hydrochloride)

CAT:

804-HY-163210

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CAS Number: 2758431-94-4
UNSPSC Description: Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride (ZJT1) is an E3 ubiquitin ligase cereblon based on Pomalidomide (HY-10984) (CRBN) ligand for recruitment of cereblon protein. Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride can be linked to protein ligand by linker to form PROTAC[1].
Target Antigen: Ligands for E3 Ligase
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/pomalidomide-5-fluoro-6-piperazine-4-methylpiperidine-hydrochloride.html
Solubility: 10 mM in DMSO
Smiles: O=C1NC(C(CC1)N2C(C3=CC(F)=C(N4CCN(CC5CCNCC5)CC4)C=C3C2=O)=O)=O.Cl.Cl
Molecular Weight: 530.42
References & Citations: [1]Meng YL, et al. Novel polycyclic compound, composition and application thereof. CN115894450A. 2023-04-04.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-163210	Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine (hydrochloride)
HY-160244	Pomalidomide 5'-piperazine-4-methylpiperidine (dihydrochloride)
HY-157566	Lenalidomide 5'-piperazine-4-methylpiperidine (hydrochloride)
HY-148834	Pomalidomide-piperazine
HY-145755-03	Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine
HY-145755-01	Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine
HY-145755-04	Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine
HY-145755-02	Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine
HY-155260	Pomalidomide-5-C4-NH2 (hydrochloride)
HY-155264	Pomalidomide-5-C8-NH2 (hydrochloride)

Cat	Name
7471/25	Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine
7469/25	Pomalidomide 5'-piperazine-4-methylpiperidine
7470/25	Pomalidomide 5'-fluoro-6'-piperazine
PC409056	4-Fluoro-4-methylpiperidine hydrochloride
7473/25	Lenalidomide 5'-piperazine-4-methylpiperidine
7468/25	Pomalidomide 5'-piperazine
7999/25	PAG 4'-piperazine-4-methylpiperidine
7997/25	PAG 3'-piperazine-4-methylpiperidine
PC3526	1-(4-Fluoro-2-nitrophenyl)-2-methylpiperidine hydrochloride
T62461-1g	Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine