Lenalidomide 5'-piperazine-4-methylpiperidine (hydrochloride)

• UNSPSC Description:

  Lenalidomide 5'-piperazine-4-methylpiperidine hydrochloride is a functionalized cerebellar ligand for PROTAC development, combining E3 ligand and terminal piperidine for subsequent chemical reactions. A protein degradant with a rigid connector is generated[1].

• Target Antigen:

  Ligands for E3 Ligase

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/lenalidomide-5-piperazine-4-methylpiperidine-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1NC(C(CC1)N2C(C3=CC=C(N4CCN(CC5CCNCC5)CC4)C=C3C2)=O)=O.Cl.Cl

• Molecular Weight:

  498.45

• References & Citations:

  [1]Yi Chen, et al. Mdm2 degrader. WO2023230059A1.2023-11-30.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2520105-60-4