SARS-CoV-2 Mpro-IN-13

SARS-CoV-2 Mpro-IN-13

• UNSPSC Description: SARS-CoV-2 Mpro-IN-13 (compound 20j) is a covalent SARS-CoV-2 Protease Mpro inhibitor with an IC50 value of 19.0 nM. SARS-CoV-2 Mpro-IN-13 processes antiviral activity with an EC50 value of 138.1 nM[1].
• Target Antigen: SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-mpro-in-13.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1CCC(F)(F)CC1)N[C@H](C2CCCCC2)C(N[C@H](COC)C(NC3(C(C(NCC4=NC=CS4)=O)=O)CCC3)=O)=O
• Molecular Weight: 625.73
• References & Citations: [1]Huang Q,et al. Discovery of α-Ketoamide inhibitors of SARS-CoV-2 main protease derived from quaternized P1 groups. Bioorg Chem. 2023 Dec 6;143:107001.|[2]Qiao Huang, et al. Discovery of α-Ketoamide inhibitors of SARS-CoV-2 main protease derived from quaternized P1 groups. Bioorg Chem. 2023 Dec 6:143:107001.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported