ATAD2-IN-1

• UNSPSC Description:

  ATAD2-IN-1 (compound 19f) is a potent ATAD2 inhibitor (IC50: 0.27 μM) and can induce apoptosis. ATAD2-IN-1 also inhibits c-Myc activation and BT-549 cell migration[1].

• Target Antigen:

  Apoptosis; c-Myc; Epigenetic Reader Domain

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/atad2-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(CN1C=NC2=C1N(C(N(C2=O)C)=O)C)NC(C=C(C=C3)C(NC4CCCC4)=O)=C3OC

• Molecular Weight:

  454.48

• References & Citations:

  [1]Yao D, et al. Fragment-based design, synthesis and biological evaluation of theophylline derivatives as ATAD2 inhibitors in BT-549 cells. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2242601.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3004556-06-0