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ATAD2-IN-1

CAT: 0804-HY-163108Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163108Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ATAD2-IN-1 (compound 19f) is a potent ATAD2 inhibitor (IC50: 0.27 μM) and can induce apoptosis. ATAD2-IN-1 also inhibits c-Myc activation and BT-549 cell migration[1].
CAS Number
3004556-06-0
UNSPSC
12352005
Target
Apoptosis; c-Myc; Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atad2-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(CN1C=NC2=C1N(C(N(C2=O)C)=O)C)NC(C=C(C=C3)C(NC4CCCC4)=O)=C3OC
Molecular Formula
C22H26N6O5
Molecular Weight
454.48
References & Citations
[1]Yao D, et al. Fragment-based design, synthesis and biological evaluation of theophylline derivatives as ATAD2 inhibitors in BT-549 cells. J Enzyme Inhib Med Chem. 2023 Dec;38 (1) :2242601.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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