Indecainide (hydrochloride)

• UNSPSC Description:

  Indecainide hydrochloride is a potent and orally active class I local anesthetic antiarrhythmic agent. Indecainide hydrochloride has Na+-channel-blocking activity[1][2][3].

• Target Antigen:

  Sodium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/indecainide-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1(CCCNC(C)C)C2=C(C3=C1C=CC=C3)C=CC=C2)N.Cl

• Molecular Weight:

  344.88

• References & Citations:

  [1]Steinberg MI, et al. Electrophysiological studies of indecainide hydrochloride, a new antiarrhythmic agent, in canine cardiac tissues. J Cardiovasc Pharmacol. 1984 Jul-Aug;6(4):614-21.|[2]Sandusky GE Jr, et al. Toxicology of indecainide hydrochloride after intravenous administration to rats and dogs. Toxicol Lett. 1985 Aug;26(2-3):107-10.|[3]D R Holland, et al. Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. J Cardiovasc Pharmacol. 1989 Sep;14(3):454-61.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Launched

• CAS Number:

  73681-12-6