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Indecainide (hydrochloride)

CAT: 0804-HY-16259Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-16259Size:1 Each
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Description
Indecainide hydrochloride is a potent and orally active class I local anesthetic antiarrhythmic agent. Indecainide hydrochloride has Na+-channel-blocking activity[1][2][3].
CAS Number
73681-12-6
Product Name Alternative
Ricainide (hydrochloride) ; LY 135837
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/indecainide-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C(C1(CCCNC(C)C)C2=C(C3=C1C=CC=C3)C=CC=C2)N.Cl
Molecular Formula
C20H25ClN2O
Molecular Weight
344.88
References & Citations
[1]Steinberg MI, et al. Electrophysiological studies of indecainide hydrochloride, a new antiarrhythmic agent, in canine cardiac tissues. J Cardiovasc Pharmacol. 1984 Jul-Aug;6 (4) :614-21.|[2]Sandusky GE Jr, et al. Toxicology of indecainide hydrochloride after intravenous administration to rats and dogs. Toxicol Lett. 1985 Aug;26 (2-3) :107-10.|[3]D R Holland, et al. Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. J Cardiovasc Pharmacol. 1989 Sep;14 (3) :454-61.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched