Indecainide

• Description :

  Indecainide (Ricainide) is an orally active antiarrhythmic agent. Indecainide can be used in the research of ventricular dysfunction. Indecainide has Na+-channel-blocking activity[1][2].

• Product Name Alternative :

  Ricainide; LY 135837 (free base)

• UNSPSC :

  12352005

• Hazard Statement :

  H315-H319-H320

• Target :

  Sodium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/indecainide.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N)C1(C2=C(C=CC=C2)C3=C1C=CC=C3)CCCNC(C)C

• Molecular Formula :

  C20H24N2O

• Molecular Weight :

  308.42

• Precautions :

  P264-P280-P302+P352-P305+P351+P338-P362

• References & Citations :

  [1]D R Holland, et al. Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. J Cardiovasc Pharmacol. 1989 Sep;14 (3) :454-61. |[2]Lindstrom T D, et al. Metabolism of the antiarrhythmic agent, indecainide, in rats, dogs, and monkeys. Drug metabolism and disposition, 1984, 12 (6) : 691-697.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [74517-78-5]