WZB117-PPG

• Description:

  WZB117-PPG is a glucose transporter 1 (GLUT1) inhibitor with anticancer activity. WZB117-PPG has remarkable photolysis efficiency and cytotoxicity to cancer cells under visible light irradiation[1].

• UNSPSC:

  12352005

• Target:

  GLUT

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/wzb117-ppg.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OCC1=CC(OC2=CC(N(CC)CC)=CC=C21)=O)OC3=CC(C(OC4=C(OC(C5=CC(OC(OCC(C6=CC=C(N(CC)CC)C=C6O7)=CC7=O)=O)=CC=C5)=O)C(F)=CC=C4)=O)=CC=C3

• Molecular Formula:

  C50H43FN2O14

• Molecular Weight:

  914.88

• References & Citations:

  [1]Geng H, et al. Photochemically Controlled Release of the Glucose Transporter 1 Inhibitor for Glucose Deprivation Responses and Cancer Suppression Research. J Proteome Res. Published online January 3, 2024.|[2]Photochemically Controlled Release of the Glucose Transporter 1 Inhibitor for Glucose Deprivation Responses and Cancer Suppression Research

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported