WZB117

• Description :

  WZB117 is a glucose transporter 1 (Glut1) inhibitor, which downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo.

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H335, H412

• Target :

  GLUT

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/WZB117.html

• Purity :

  99.93

• Solubility :

  DMSO : 250 mg/mL (ultrasonic)

• Smiles :

  OC1=CC=CC(C(OC2=CC=CC(F)=C2OC(C3=CC(O)=CC=C3)=O)=O)=C1

• Molecular Formula :

  C20H13FO6

• Molecular Weight :

  368.31

• Precautions :

  H315, H319, H335, H412

• References & Citations :

  [1]Liu Y, et al. A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo. Mol Cancer Ther. 2012 Aug;11 (8) :1672-82.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  GLUT1

• CAS Number :

  [1223397-11-2]