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Elliptinium (acetate)

CAT: 0804-HY-16189Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-16189Size:1 Each
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Description
Elliptinium acetate (NSC 264137) is a DNA intercalating agent that is highly cytotoxic to L1 210 cells and covalently binds to nucleic acids from L1210 cells. Elliptinium acetate can be used in cancer research, particularly in metastatic breast cancer[1][2].
CAS Number
58337-35-2
Product Name Alternative
NSC 264137; Celiptium
UNSPSC
12352005
Hazard Statement
H315-H319
Target
DNA Stain
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/elliptinium-acetate.html
Solubility
10 mM in DMSO
Smiles
O=C(C)[O-].OC1=CC=C2NC3=C(C)C4=C(C=[N+](C)C=C4)C(C)=C3C2=C1
Molecular Formula
C20H20N2O3
Molecular Weight
336.38
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Dugue B, et al. Covalent binding of elliptinium acetate (NSC 264137) to nucleic acids of L1210 cells in culture. Cancer Res. 1986 Aug;46 (8) :3828-33.|[2]Arteaga CL, et al. Elliptinium, a DNA intercalating agent with broad antitumor activity in a human tumor cloning system. Eur J Cancer Clin Oncol. 1987 Nov;23 (11) :1621-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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