Z-ATAD-FMK

Z-ATAD-FMK

• CAS Number: 1416658-51-9
• UNSPSC Description: Z-ATAD-FMK is an inhibitor of caspase-12. Z-ATAD-FMK is an inhibitor of caspase-12. Z-ATAD-FMK prevents endoplasmic reticulum stress-mediated apoptosis by inhibiting the activity of caspase-12 and reducing the activity of caspase-9[1].
• Target Antigen: Apoptosis; Caspase
• Type: Peptides
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/z-atad-fmk.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(CF)=O)=O)=O)[C@H](C)NC(OCC1=CC=CC=C1)=O
• Molecular Weight: 526.51
• References & Citations: [1]Zhao CQ, et al. Both endoplasmic reticulum and mitochondria are involved in disc cell apoptosis and intervertebral disc degeneration in rats. Age (Dordr). 2010 Jun;32(2):161-77.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported