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Anti-aging agent 1

CAT: 0804-HY-161088Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161088Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-aging agent 1 (compound 24) is a derivative of piperlongumine (PL). Anti-aging agent 1 exhibits a 50-fold enhancement in senolytic activity against senescent WI-38 fibroblasts compared to PL[1].
CAS Number
1884611-28-2
UNSPSC
12352005
Target
Drug Derivative; ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Others; Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/anti-aging-agent-1.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(/C=C/C(N2CCCC=C(Cl)C2=O)=O)C=C1
Molecular Formula
C16H16ClNO3
Molecular Weight
305.76
References & Citations
[1]Xuan Zhang, et al. Design and optimization of piperlongumine analogs as potent senolytics. Bioorg Med Chem Lett. 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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