Anti-neuroinflammation agent 1

• UNSPSC Description:

  Anti-neuroinflammation agent 1 is a potent anti-neuroinflammation agent that regulates polarization BV2 microglia cells from M1 phenotype to M2 phenotype[1].

• Target Antigen:

  Interleukin Related; NOD-like Receptor (NLR)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/anti-neuroinflammation-agent-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC2=C(C(OC)=C1)C3=C(CCO2)C(C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)N=C(N)N3.Cl

• Molecular Weight:

  523.86

• References & Citations:

  [1]Yang Yang, et al. Discovery of anti-neuroinflammatory agents from 1,4,5,6-tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidin-2-amine derivatives by regulating microglia polarization. Eur J Med Chem. 2023 Jul 27;259:115688.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4