AC2 selective-IN-1

• Description :

  AC2 selective-IN-1 (compound 14) is a potent (IC50=4.45 μM), non-toxic, and selective mAC2 inhibitor[1].

• UNSPSC :

  12352005

• Target :

  Adenylate Cyclase

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/ac2-selective-in-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  NC1=C2C(N(CCOCP(N[C@H](C(OC(C)C)=O)CC3=CC=CC=C3)(N[C@@H](CC4=CC=CC=C4)C(OC(C)C)=O)=O)C=C2C5=CC=CC(C(N6)=NOC6=O)=C5)=NC=N1

• Molecular Formula :

  C41H47N8O8P

• Molecular Weight :

  810.83

• References & Citations :

  [1]Pavel Kraina, et al. Discovery of a potent and selective human AC2 inhibitor based on 7-deazapurine analogues of adefovir. Bioorg Med Chem. 2023.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported