AC2 selective-IN-1

• Description:

  AC2 selective-IN-1 (compound 14) is a potent (IC50=4.45 μM), non-toxic, and selective mAC2 inhibitor[1].

• UNSPSC:

  12352005

• Target:

  Adenylate Cyclase

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/ac2-selective-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC1=C2C (N (CCOCP (N[C@H] (C (OC (C) C) =O) CC3=CC=CC=C3) (N[C@@H] (CC4=CC=CC=C4) C (OC (C) C) =O) =O) C=C2C5=CC=CC (C (N6) =NOC6=O) =C5) =NC=N1

• Molecular Formula:

  C41H47N8O8P

• Molecular Weight:

  810.83

• References & Citations:

  [1]Pavel Kraina, et al. Discovery of a potent and selective human AC2 inhibitor based on 7-deazapurine analogues of adefovir. Bioorg Med Chem. 2023.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported