AC2 selective-IN-1

CAT: 0804-HY-161021Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-161021Size:1 Each

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Description

AC2 selective-IN-1 (compound 14) is a potent (IC50=4.45 μM), non-toxic, and selective mAC2 inhibitor[1].

UNSPSC

12352005

Target

Adenylate Cyclase

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ac2-selective-in-1.html

Solubility

10 mM in DMSO

Smiles

NC1=C2C(N(CCOCP(N[C@H](C(OC(C)C)=O)CC3=CC=CC=C3)(N[C@@H](CC4=CC=CC=C4)C(OC(C)C)=O)=O)C=C2C5=CC=CC(C(N6)=NOC6=O)=C5)=NC=N1

Molecular Formula

C41H47N8O8P

Molecular Weight

810.83

References & Citations

[1]Pavel Kraina, et al. Discovery of a potent and selective human AC2 inhibitor based on 7-deazapurine analogues of adefovir. Bioorg Med Chem. 2023.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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