TRPV2-selective blocker 1

• Target:

  TRP/TRPV Channel|||Others

• Related Pathways:

  Others|||Membrane transporter/Ion channel

• Bioactivity:

  TRPV2-selective blocker 1 (compound IV2-1) is a selective inhibitor of the TRPV2 channel, with an IC50 value of 6.3 ?M, specifically targeting the TRPV2 channel without affecting TRPV1, TRPV3, or TRPV4 channels, and effectively suppresses TRPV2-mediated calcium influx in macrophages, inhibiting their phagocytic activity [1].

• Smiles:

  O=C(C)CC(C(=C1SCCS1)C=2C=CC=CC2)C

• Molecular Formula:

  C15H18OS2

• Molecular Weight:

  278.43

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2242724-49-6