BI-8668

• UNSPSC Description:

  BI-8668 (compound 40) is an inhibitor of ENaC. BI-8668 can be used in the study of cystic fibrosis[1].

• Target Antigen:

  Sodium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/bi-8668.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=NC(Cl)=CN=C1N)NCC2=[N+](CC)C3=C(C=CC(C(N(CCN(C)C)C)=O)=C3)N2CC.[Cl-]

• Molecular Weight:

  523.46

• References & Citations:

  [1]Betzemeier B, et al. Discovery and development of BI 1265162, an ENaC inhibitor for the treatment of cystic fibrosis. Eur J Med Chem. 2023 Dec 18;265:116038.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2084059-97-0