INX-SM-3

• Description :

  INX-SM-3 is a novel glucocorticosteroid . INX-SM-3 can be used as a glucocorticosteroid-linker connected to ADCs[1].

• UNSPSC :

  12352203

• Target :

  Glucocorticoid Receptor

• Type :

  ADC Related

• Related Pathways :

  Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/inx-sm-3.html

• Purity :

  99.50

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@@H](C6=CC=C(C=C6)CC78CC(C7)(C8)N)O2)C)=O

• Molecular Formula :

  C34H41NO6

• Molecular Weight :

  559.69

• References & Citations :

  [1]Jay ROTHSTEIN, et al. NOVEL STEROID PAYLOADS, STEROID LINKERS, ADCs CONTAINING AND USE THEREOF. WO2022150637A1. 2022.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, stored under nitrogen)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• CAS Number :

  [2734877-96-2]