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PIM-IN-2

CAT: 0804-HY-160006Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-160006Size:1 Each
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Description
PIM-IN-2 (Pim-2) is a Pim kinases inhibitor (IC50 = 25 nM) . PIM-IN-2 promotes cell survival, is antiapoptotic, and has exhibited an elevated level of expression in a variety of human tumors[1].
CAS Number
1006699-45-1
UNSPSC
12352005
Target
Pim
Type
Reference compound
Related Pathways
JAK/STAT Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pim-in-2.html
Solubility
10 mM in DMSO
Smiles
OC(/C=C/C1=CC=CC(C2=NC(NCC3CCNCC3)=CN=C2)=C1)=O
Molecular Formula
C19H22N4O2
Molecular Weight
338.40
References & Citations
[1]Qian K, et al. Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode [J]. Journal of medicinal chemistry, 2009, 52 (7) : 1814-1827.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PIM2

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