PR antagonist 1

• UNSPSC Description:

  PR antagonist 1 (compound 8) is a selective progesterone receptor (PR) antagonist, and can be used for the research of a variety of progesterone-related diseases and disorders such as endometriosis and uterine fibroids[1].

• Target Antigen:

  Progesterone Receptor

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/pr-antagonist-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=C(C)C=C(OC2=C(C3CC3)N(CS(=O)(C)=O)N=C2C)C=C1C

• Molecular Weight:

  359.44

• References & Citations:

  [1]Paul A, et al. Development of a Practical Synthesis of the Progesterone Receptor Antagonist 4-{[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy}-2,6-dimethylbenzonitrile, Organic Process Research & Development 2009 13 (5), 848-853.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  936345-34-5