CBR1-IN-6

• UNSPSC Description:

  CBR1-IN-6 (compound 1a) is a CBR1 inhibitor with chemosensitizing and cardioprotective activities[1].

• Target Antigen:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cbr1-in-6.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC1=CC=C(/C=C/C(N2CCC(O)CC2)=O)C=C1

• Molecular Weight:

  265.74

• References & Citations:

  [1]Paulina Koczurkiewicz-Adamczyk, et al. Cinnamamide derivatives with 4-hydroxypiperidine moiety enhance effect of doxorubicin to cancer cells and protect cardiomyocytes against drug-induced toxicity through CBR1 inhibition mechanism. Life Sci. 2022 Sep 15:305:120777.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported