CBR1-IN-3

• Description :

  CBR1-IN-3 (compound 13h) is a potent inhibitor of carbonyl reductase 1 (CBR1), with IC50 value of 0.034 μM[1].

• UNSPSC :

  12352005

• Target :

  NADPH Oxidase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/cbr1-in-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C(C1=N)=CC2=C(O1)C(O)=CC=C2)NC3=CC=CC=C3Cl

• Molecular Formula :

  C16H11ClN2O3

• Molecular Weight :

  314.72

• References & Citations :

  [1]Dawei Hu, et al. Synthesis of 8-hydroxy-2-iminochromene derivatives as selective and potent inhibitors of human carbonyl reductase 1. Org Biomol Chem. 2015 Jul 21;13 (27) :7487-99.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [891101-69-2]