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SARS-CoV-2-IN-72

CAT: 0804-HY-157439Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157439Size:1 Each
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Description
SARS-CoV-2-IN-72 (compound 12) is a potent allosteric inhibitor of the SARS-COV-2 papain-like protease domain that can trigger the degradation of NSP3[1].
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-in-72.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(CNC(C2CCN(C(C)C3=CC=CC4=CC=CC=C43)CC2)=O)=CC=C1)NCC5=NC=CN=C5
Molecular Formula
C31H33N5O2
Molecular Weight
507.63
References & Citations
[1]Peter E Cockram, et al. Allosteric Inhibitors of the SARS-COV-2 Papain-like Protease Domain Induce Proteasomal Degradation of Its Parent Protein NSP3. ACS Chem Biol. 2023 Dec 27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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