ICMT-IN-8

• Description:

  ICMT-IN-8 (compound 30) is an inhibitor of ICMT (IC50=0.652 μM) [1].

• UNSPSC:

  12352005

• Target:

  ICMT

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/icmt-in-8.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC=C (C=C1OC) NCCC2 (C3=CC=CC=C3) CC (C) (C) OCC2

• Molecular Formula:

  C23H31NO3

• Molecular Weight:

  369.50

• References & Citations:

  [1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1313602-76-4