TTNPB (Standard)

• Description:

  TTNPB (Standard) is the analytical standard of TTNPB. This product is intended for research and analytical applications. TTNPB is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC50s of α=5.1 nM, β= 4.5 nM, and γ=9.3 nM, respectively.

• Product Name Alternative:

  Ro 13-7410 (Standard) ; Arotinoid acid (Standard) ; AGN191183 (Standard)

• UNSPSC:

  12352005

• Target:

  Apoptosis; Autophagy; RAR/RXR; Reference Standards

• Related Pathways:

  Apoptosis; Autophagy; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Cancer

• Smiles:

  O=C(O)C1=CC=C(/C=C(C2=CC=C3C(C)(C)CCC(C)(C)C3=C2)\C)C=C1

• Molecular Formula:

  C24H28O2

• Molecular Weight:

  348.48

• References & Citations:

  [1]Pignatello MA, et al. Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410) : binding affinities and disposition. Toxicol Appl Pharmacol. 1997 Feb;142 (2) :319-27.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [71441-28-6]