Cbl-b-IN-9

Cbl-b-IN-9

• CAS Number: 2815223-41-5
• UNSPSC Description: Cbl-b-IN-9 (Compound 300) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 5.6 nM and 4.7 nM, respectively[1].
• Target Antigen: E1/E2/E3 Enzyme
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cbl-b-in-9.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=C(CN1C3=CC(C4(CC5=NN=CN5C)COC4)=CC(C6CC6)=N3)C(C(F)(F)F)=CC(CNC7(CCC7)C)=C2
• Molecular Weight: 566.62
• References & Citations: [1]Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported