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Cbl-b-IN-9

CAT: 0804-HY-156765Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156765Size:1 Each
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Description
Cbl-b-IN-9 (Compound 300) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 5.6 nM and 4.7 nM, respectively[1].
CAS Number
2815223-41-5
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cbl-b-in-9.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(CN1C3=CC(C4(CC5=NN=CN5C)COC4)=CC(C6CC6)=N3)C(C(F)(F)F)=CC(CNC7(CCC7)C)=C2
Molecular Formula
C30H33F3N6O2
Molecular Weight
566.62
References & Citations
[1]Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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